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Methylcobalamin is a form of vitamin B12 that is used to treat vitamin B12 deficiency, peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis. It is the active form of methylcobalamin and vitamin b12 that is used in adults alone or in combination with other vitamins as a dietary supplement.

Methylcobalamin is equivalent physiologically to vitamin B12 and can be used to prevent or treat pathology arising from a lack of vitamin B12 intake.


Methylcobalamin, also known as vitamin b12 methylcobalamin , is an important vitamin needed for the brain, nerves, and production of red blood cells in the body. Methylcobalamin is made both in the body and created within a laboratory for supplemental purposes. Methylcobalamin can also be found in foods, such as clams, mollusks, liver, fish, lamb, veal, beef, and dairy products. Vitamin B12 deficiency is rare in healthy individuals; it is more commonly found in the elderly and those with strict diets or gastrointestinal conditions.

Prolonged B12 deficiency can impair red blood cell production, leading to anemia, along with possible gastrointestinal issues and nerve damage. Methylcobalamin is used to treat not only vitamin B12 deficiency but also other conditions, such as pernicious anemia and diabetes. It also helps increase metabolic energy and improve mood regulation. Some clinical trials are also testing its use in people with dementia as well. buy b12 injections online supplements contain cyanocobalamin, which is another form of B12 not found naturally. Cyanocobalamin is popular as it's both a stable and cost-effective form of B12. However, in order for the B12 to be utilized in the body, the liver must convert the cyanocobalamin to a biologically active and tissue-ready form, either by converting it to adenosylcobalamin or attaching it to a methyl group to form methylcobalamin. By choosing to supplement with methylcobalamin, one can circumvent this detox process. Research shows that methylcobalamin is more efficiently used and retained in the body than cyanocobalamin.

Benefits :
  • Neurological Health

    Methylcobalamin is essential for the maintenance of the nervous system. It supports the formation and maintenance of myelin, a protective sheath around nerve fibers. Adequate levels of methylcobalamin are crucial for nerve function, and its deficiency can lead to neurological symptoms such as numbness, tingling, and difficulty walking.

  • Energy Production

    Vitamin B12, including methylcobalamin, is involved in the metabolism of fats and carbohydrates, playing a role in the conversion of food into energy. Adequate levels of B12 are important for overall energy production and can help prevent fatigue and weakness.

  • Red Blood Cell Formation

    Methylcobalamin is essential for the synthesis of DNA, which is crucial for the formation and maturation of red blood cells in the bone marrow. A deficiency in methylcobalamin can lead to anemia and associated symptoms such as fatigue and weakness.

  • Cognitive Function

    Some studies suggest that adequate levels of vitamin B12, including methylcobalamin, may be associated with better cognitive function. B12 is involved in the production of neurotransmitters and the maintenance of healthy brain cells, and its deficiency has been linked to cognitive decline and an increased risk of neurodegenerative diseases.

  • Cardiovascular Health

    Methylcobalamin is involved in the conversion of homocysteine to methionine, helping to lower homocysteine levels. Elevated homocysteine is associated with an increased risk of cardiovascular disease. By participating in this metabolic process, methylcobalamin may contribute to cardiovascular health.

Precautions :
  • Allergies and Sensitivities

    Individuals with known allergies or sensitivities to vitamin B12 or any of the components of Methylcobalamin supplements should avoid its use. It's crucial to read the product labels and consult with a healthcare professional if there are concerns about potential allergic reactions.

  • Interaction with Medications

    Methylcobalamin supplements may interact with certain medications, affecting their absorption or effectiveness. People taking medications such as chloramphenicol, proton pump inhibitors (PPIs), and certain anticonvulsants should consult with their healthcare provider before using Methylcobalamin to avoid potential interactions.

  • Kidney Disease

    Individuals with kidney disease should exercise caution when using Methylcobalamin supplements. The kidneys play a role in the elimination of excess vitamin B12, and impaired kidney function may lead to an accumulation of the vitamin in the body. Dosage adjustments may be necessary under the supervision of a healthcare professional.

  • Leber's Disease

    Methylcobalamin supplements should be avoided in individuals with Leber's disease, a hereditary eye disease that can cause optic nerve atrophy. Vitamin B12 supplementation, including Methylcobalamin, may exacerbate optic nerve damage in people with this condition.

  • Pregnancy and Breastfeeding

    Pregnant and breastfeeding women should consult with their healthcare provider before using Methylcobalamin supplements. Adequate vitamin B12 is crucial for the developing fetus and breastfeeding infants, but it's important to ensure that supplementation is appropriate and in line with recommended dosages.

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